Study database
Follows a group over time. It shows associations, never a cause: the decisive difference often sits outside what was measured.
HOHorse
In 263 National Hunt horses a tendon change was found in 24 per cent of cases over two seasons, with a spread between training yards of 10 to 40 per cent that was classed as not established; routine ultrasound at three-month intervals could not predict the acute rupture.
HOHorse
In 113 racehorses followed up, the re-injury rate after cell implantation was 27.4 per cent, and 25.7 per cent in National Hunt horses, which was lower than in published historical comparison groups.
HOHorse
In 122 air-transported Warmblood sport horses, a serum amyloid A cut-off of 23 micrograms per millilitre 24 hours after arrival separated healthy from sick animals with about 93 per cent sensitivity and 91 per cent specificity, while rectal temperature identified only about 3 per cent of the sick animals; two co-authors were employed by the manufacturer of the rapid test used.
HOHorse
Retrospective cohort of 397 newborn foals: septic animals had a median value of 114 micrograms per millilitre against 1.5 in sick non-septic and 0 in healthy foals; at the threshold of 100 the specificity was 97.5 per cent, but the sensitivity only 52.9 per cent.
HOHorse
In 176 adult horses with acute colitis the serum amyloid A value on admission did not differ between survivors (median 548 milligrams per litre) and non-survivors (396); what carried prognostic information were lactate, heart rate, age and a duration of colic of more than 24 hours.
HOHorse
Only the respirable and not the inhalable dust fraction was linked to the proportion of neutrophils, and higher mast cell and neutrophil proportions went with measurably poorer racing performance.
HOHorse
In 941 out-of-hours cases, 23.9 per cent were critical and 18 per cent of the horses were put down; a raised heart rate, age and an altered mucous membrane colour remained associated with the critical outcome in the joint analysis.
HOHorse
Over one year on 31 premises with 1,427 horses, the crude incidence was 10.6 colic cases per 100 horse years, three quarters of the episodes were mild, and 28 per cent of all deaths were due to colic, more than to any other single cause.
HOHorse
In the same cohort, a previous colic, changes in concentrate and hay feeding and large amounts of concentrate were associated with markedly raised odds of colic, while premises-level characteristics made no independent contribution.
HOHorse
Among 896 Thoroughbred mares with surgically treated large colon volvulus, 88 per cent survived to discharge, and the duration of colic signs before admission was independently associated with survival, the median of that duration being two hours.
HOHorse
Of 375 colic horses treated, 88 per cent survived to discharge, 91 per cent of those treated medically and 77 per cent of those treated surgically, with small intestinal lesions carrying a worse prognosis than large intestinal lesions.
HOHorse
Of 244 horses operated on, 203 were discharged and 176 followed for at least four years: 44.8 per cent developed complications after discharge, most often further colic, and a higher complication score before discharge went with lower long-term survival.
HOHorse
Among 47,396 general anaesthetics from 93 centres in 28 countries, the death rate within seven days was 4.2 per cent for colic procedures against 0.6 per cent without colic, compared with 7.8 per cent in the previous survey from 2002.
HOHorse
In a nine-month field study with 66 horses on one yard, the frequency of colic and lameness was lower in the active open barn than in single boxes (0 against 5 per cent and 18 against 26 per cent respectively), while more wounds occurred, without more lost training.
HOHorse
In 35 horses undergoing colic surgery, total magnesium was below the reference range in 17 per cent and ionised magnesium in 54 per cent before the operation; total values were considerably less sensitive for detecting a deficiency.
HOHorse
Among 75 sick and 26 healthy horses, hypomagnesaemia occurred in 47 per cent of animals with obstructive intestinal disease against 4 per cent of controls; unlike in human intensive care patients, it was not linked to mortality.
HUHuman
Combining sequencing with cell counting revealed microbial loads differing by up to tenfold between healthy people; the familiar contrast between Bacteroides and Prevotella turned out to be an artefact of the relative-abundance representation.
SPSpecies-independent
236 publications from endorsing and non-endorsing journals: in 2015 both groups stood at around 60 per cent of items fully reported, with no difference between the groups; not a single paper reported every item, and bias-relevant information was missing particularly often.
Once a month: new syntheses, checked studies, and what has changed in the state of the evidence.